Antithrombotic Treatment in Neonatal Cerebral Sinovenous Thrombosis: Results of the International Pediatric Stroke Study
نویسندگان
چکیده
منابع مشابه
Cerebral sinovenous thrombosis during asparaginase treatment
A boy (age: 71/12 years) with acute lymphoblastic leukaemia developed thrombosis of the sinus sagitalis superior with secondary haemorrhagic infarction while on induction treatment with vincristine, prednisone, and asparaginase. Based on this report, the potential pathogenic mechanisms are discussed with respect to congenital prothrombotic defects as well as to the role of antileukaemic treatme...
متن کاملCerebral Sinovenous Thrombosis
Cerebral sinovenous thrombosis (CSVT) is a rare but serious cerebrovascular disorder affecting children from the newborn period through childhood and adolescence. The incidence is estimated at 0.6/100,000/year, with 30-50% occurring in newborns. Causes are diverse and are highly age dependent. Acute systemic illness is the dominant risk factor among newborns. In childhood CSVT, acute infections...
متن کاملNeonatal cerebral sinovenous thrombosis from symptom to outcome.
BACKGROUND AND PURPOSE Cerebral sinovenous thrombosis is a rare disease with severe neurological sequelae. The aim of this retrospective multicenter study was to investigate the clinical course, possible risk factors, and outcome of a cohort of neonatal patients with sinovenous thrombosis and, second, to estimate the incidence in The Netherlands. METHODS From January 1999 to March 2009, a rev...
متن کاملSymptomatic neonatal arterial ischemic stroke: the International Pediatric Stroke Study.
BACKGROUND Neonatal arterial ischemic stroke (AIS) has emerged as a leading cause of perinatal brain injury, cerebral palsy, and lifelong disability. The pathogenesis is poorly understood, which limits the development of treatment and prevention strategies. Multicenter studies must define epidemiology, risk factors, treatment practices, and outcomes to advance clinical trials and improve the ad...
متن کاملAnticoagulants in pediatric cerebral sinovenous thrombosis: a safety and outcome study.
OBJECTIVE Clinical trials are lacking in pediatric cerebral sinovenous thrombosis (CSVT). Neonates and children increasingly receive anticoagulant therapy (ACT) based on adult studies. Safety data for ACT in pediatric CSVT are scant and urgently needed. The objective was to assess the safety and outcome of ACT in pediatric CSVT. METHODS In a single-center prospective study, neonates and child...
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ژورنال
عنوان ژورنال: The Journal of Pediatrics
سال: 2010
ISSN: 0022-3476
DOI: 10.1016/j.jpeds.2009.11.061